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CD35兔單克隆抗體

CD35兔單克隆抗體

  • 價(jià)格￥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150187
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150187CD35兔單克隆抗體100ul支600
CD35
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# BX50064?Clone# ?BP6069
Predicted?Molecular Wt:
224kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P17927
Background:
CD35,complement?receptor?1,?is a cell?membrane-bound,?monomeric glycoprotein on?numerous cell?types?including
erythrocytes,?leukocytes, glomerular?podocytes, and follicular dendritic cells. The?primary?function?of?CD35?is?to?serve?as?the???cellular?receptor for C3band C4b, the?most?important components?of the?complement?system?leading to?clearance?of foreign?macromolecules.
CD35 antigen?is found on erythrocytes,?B?cells,?a?subset?of T cells,?monocytes,?as?well?as?eosinophils,?and?neutrophils.?Anti-
CD35?is considered a?mature?B-cell?marker which?labels follicular dendritic?reticulum?cells?and tumors?derived?from?such?cells?such as follicular dendritic?cell tumor/sarcoma.
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to CD35?residues?within?aa1939-2039 of??CD35?was?used?as?an
immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.??Biddle?DA?etal.?Mod?Pathol.?2002 Jan;15(1):50-8.
2. ?Dogan?A?et?al. Am?J?Surg?Pathol.?2003 Jul;27(7):903-11.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of tonsil?tissue?labelling?CD35
with?BP6069.?Heat mediated?antigen
retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

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