CD23兔單克隆抗體

價格￥600
規(guī)格100ul
貨號HKZ150167
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150167	CD23兔單克隆抗體	100ul	支	600

CD23
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50044?Clone# ?BP6049
Predicted?Molecular Wt:
36kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P06734
Background:
CD23 antigen?is a transmembrane glycoprotein?by various?hematopoietic cell?types?and?functions?as?a?low-affinity?receptor?for?IgE. CD23?is?involved?in?regulating?IgE?production and?has other?potential?biologic functions,?including?promoting the?survival????of germinal center?B?lymphocytes.
CD23?is found?in some?mature?B-cell?lymphomas and?in?Reed-Sternberg cells?in?Hodgkin?disease.?Follicular?dendritic cells?and??some activated?B-cells within germinal centers express?CD23?in?high?density?and?mantle?zone?B-cells?are?stained?weakly. The???majority of chronic?lymphocytic?leukemias/small?lymphocytic?lymphomas are CD23?positive, whereas?mantle?cell?lymphomas?are generally?negative.
CD23?has?been shown to?be?useful for the differentiation of?small?lymphocytic?lymphomas?and?mantle?cell?lymphoma.
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to CD23?residues
within?aa221-321 of?CD23 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Olteanu?H, et?al. Am?J?Clin?Pathol.?2011 Jan;135(1):46-?53.
2. ?Kumar?S, et?al.?Mod?Pathol.?1996?Sep;9(9):925-9.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of
tonsil tissue?labelling
CD23 with?BP6049.?Heat mediated?antigen
retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

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