亚洲AV第二区国产精品,最好的2019中文大全在线观看 ,黄色视频网站在线观看,国产裸体美女永久免费无遮挡
AFP兔單克隆抗體

AFP兔單克隆抗體

  • 價格￥600
  • 規(guī)格100ul
  • 貨號HKZ150390
  • 單位支
  • 品牌HaoKebio

產(chǎn)品介紹
產(chǎn)品參數(shù)
資料下載
品牌商品編碼商品名稱規(guī)格單位單價
HaoKebioHKZ150390AFP兔單克隆抗體100ul支600
AFP
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50267?Clone# ?BP6244
Predicted?Molecular Wt:
67kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P02771
Background:
Alpha-fetoprotein?(AFP)?is a?65?kDa glycoprotein found?in the?mammalian fetal?liver, yolksac, and?GI?tract.?While?AFP
expression?in?adult cells?is?low,?it?is aberrantly expressed?in?adult?liver cancer?cells.?The?tumor?suppressor?gene?p53?and?β-?????catenin are?both?involved?in the?regulation?of AFP expression.?In?normal?adult?cells,?p53?binds to?the?repressor?region?of the?AFP gene, thereby?blocking transcription.?Mutations?in?both?p53 and?β-catenin are associated?with?aberrant?expression?of????AFP.?Research studies?have shown that elevated serum?AFP?levels?are?predictive?of?hepatocellular?carcinoma.
AFP?is?not expressed?in?adult?liver tissue,?but?it?is aberrantly expressed?in?adult?liver?cancer?cells.?AFP?is?mainly?used?in clinical diagnosis of?hepatocellular carcinoma.
Subcellular?location:
Cytoplasmic
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?Meier, V. et?al.?(2006) Comp?Hepatol?5,?2.
2. ?Peng, S.Y. et?al.?(2004)?Int?J?Cancer?112,?44-50.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of ?hepatocellular?carcinoma?labelling?AFP?with?BP6244.?

暫無

說明文檔下載

上一篇: 下一篇:

推薦

您好！請登錄

點擊取消回復(fù)
    展開更多
    點擊展開我們的聯(lián)系方式