TROP-2兔單克隆抗體

價格￥2200
規(guī)格100ul
貨號HKZ150354
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150354	TROP-2兔單克隆抗體	100ul	支	2200

TROP-2
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50231?Clone# ?BP6208
Predicted?Molecular Wt:
36kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P09758
Background:
TROP-2 or Tumor-associated calcium signal transducer?2,?also?known?as epithelial?glycoprotein-1?antigen?(EGP-1),?is?a?protein?that?in?humans?is encoded?by the TACSTD2 gene. This transmembrane glycoprotein functions?in?a variety?of?cell?signaling
pathways and was first elucidated as?a transducer?of?an?intracellular?calcium?signal..
TROP-2?is expressed?in a variety of epithelial?tissues?and?tumor?tissues?from?which?TROP2?originates,?such?as?tonsil,?esophagus,?pancreatic,?prostate and gastric cancers.
TROP-2?has?become a?new target for?researchers to develop antibody-conjugated?drugs. TROP-2?is?highly?expressed?in?triple-??negative?breast cancer,?non-small cell?lung cancer,?uroepithelial carcinoma?and various?types?of?solid?tumors,?and?is?expected
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer
(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)
for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA
0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store
at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ?McDougall, A.R. et?al.?(2015)?Dev?Dyn?244,?99-109.
2.?Shvartsur, A. and?Bonavida,?B.?(2015) Genes?Cancer?6,?84-105.
Immunohistochemistry
(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of
human?esophageal?carcinoma
tissue?labelling TROP-2 with
BP6208.?Heat?mediated?antigen retrieval?was?performed?using????Tris/EDTA?buffer?pH?9.0

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