\n
\n![\"Cytokeratin](\"https:\/\/www.haokebio.com\/wp-content\/themes\/smartenterprise\/images\/loading.png\")
<\/a><\/div><\/div>
![\"Cytokeratin](\"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016152144405.png?imageView2\/0\/format\/webp\/q\/75\")
<\/a><\/div><\/div>\nCytokeratin 8&18\u5154\u5355\u514b\u9686\u6297\u4f53Cocktail<\/h1><\/div>
Cytokeratin 8&18\u5154\u5355\u514b\u9686\u6297\u4f53Cocktail<\/h1><\/div><\/i>\u4e00\u6297<\/a> \u6297\u4f53<\/a> \u8bd5\u5242<\/a> <\/span><\/div><\/header>- \u4ef7\u683c<\/span>\u00a5600<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150268<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150268<\/th> Cytokeratin 8&18\u5154\u5355\u514b\u9686\u6297\u4f53Cocktail<\/th> 100ul<\/th> \u652f<\/th> 600<\/th><\/tr><\/tbody><\/table>Cytokeratin\u00a08&18<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50145 Clone#\u00a0\u00a0<\/strong>BP6005&BP6054
Predicted\u00a0Molecular Wt:<\/strong>
54\/48kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P05787\/P05783
Background:<\/strong>
Cytokeratin\u00a018\u00a0is a type\u00a0Icytokeratin.\u00a0It\u00a0is, together with\u00a0its filament\u00a0partner cytokeratin\u00a08,\u00a0perhaps the\u00a0most\u00a0commonly\u00a0found\u00a0products of the\u00a0intermediate filament gene family.
In some epithelial cell types, cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0are\u00a0the\u00a0sole\u00a0keratins\u00a0present.\u00a0The\u00a0classical\u00a0example\u00a0is\u00a0the\u00a0liver,\u00a0with cytokeratin 8\/cytokeratin\u00a018\u00a0representing the characteristic and\u00a0only\u00a0keratin\u00a0pair\u00a0of\u00a0normal\u00a0hepatocytes.\u00a0The\u00a0same\u00a0is
true for other\u00a0highly specialized\u00a0parenchymatous epithelia such\u00a0asacinar\u00a0cells\u00a0of the\u00a0pancreas,\u00a0proximal\u00a0tubular\u00a0epithelial
cells of the\u00a0kidney, and certain endocrine\u00a0cells\u00a0such\u00a0as\u00a0pancreatic\u00a0islet\u00a0cells.\u00a0Furthermore,\u00a0cytokeratin\u00a08\/cytokeratin\u00a018\u00a0occur\u00a0together\u00a0with\u00a0other\u00a0keratins\u2014in\u00a0various\u00a0pseudostratified\u00a0(e.g.\u00a0respiratory) and\u00a0complex\u00a0(e.g.\u00a0glandular)\u00a0epithelia\u00a0and\u00a0in\u00a0the \u00a0\u00a0urothelium;\u00a0in these composite epithelial tissues, cytokeratin\u00a08\u00a0and\u00a0cytokeratin18\u00a0are\u00a0often\u00a0most\u00a0prominent\u00a0in the\u00a0lumen-
lining cells.\u00a0Even\u00a0in\u00a0non-keratinizing stratified squamous epithelia,\u00a0cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0may\u00a0be focally\u00a0expressed\u00a0in the\u00a0basal cell\u00a0layer, together with cytokeratin\u00a019\u00a0and the\u00a0constitutive\u00a0stratified-epithelial\u00a0keratins.
In\u00a0regard to\u00a0malignant tumors, cytokeratin 8 and\u00a0cytokeratin\u00a018\u00a0are\u00a0expressed\u00a0in\u00a0most\u00a0carcinomas\u00a0except\u00a0for\u00a0some\u00a0differentiated squamous cell carcinomas. Therefore, cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0antibody\u00a0strongly\u00a0stain\u00a0most\u00a0\u00a0adenocarcinomas,\u00a0hepatocellular carcinomas,\u00a0renal cell carcinomas, and\u00a0neuroendocrine\u00a0carcinomas.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide corresponding\u00a0to cytokeratin 8
residues\u00a0within\u00a0aa383\u2010C\u00a0terminal\u00a0of\u00a0cytokeratin\u00a08\u00a0was used as\u00a0an\u00a0immunogen.
Synthetic\u00a0peptide corresponding to cytokeratin\u00a018
residues\u00a0within\u00a0aa330-430 of\u00a0cytoketatin\u00a018\u00a0was\u00a0used as an\u00a0immunogen.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Storage instructions:<\/strong>
Shipped on\u00a0blue\u00a0ice.\u00a0Upon delivery,\u00a0aliquot,\u00a0and\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0-18\u00b0C. Avoid\u00a0freeze\u00a0\/\u00a0thaw\u00a0cycles.
Recommended\u00a0Dilutions:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:50-1:100
Background\u00a0References:<\/strong>
1.\u00a0Wiedenmann\u00a0B,\u00a0et.al.\u00a0Proc\u00a0Natl\u00a0Acad\u00a0Sci\u00a0U\u00a0S\u00a0A.\u00a01986\u00a0May;83(10):3500-4.
2.\u00a0Quinn\u00a0B. Am\u00a0J\u00a0Surg\u00a0Pathol.\u00a01998\u00a0May;22(5):550-6.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed
paraffin-embedded sections)\u00a0analysis of\u00a0colon
tissue\u00a0labelling\u00a0Cytokeratin\u00a0\u00a0\u00a0\u00a08&18 with\u00a0BP6005&BP6054.\u00a0Heat\u00a0mediated\u00a0antigen
retrieval\u00a0was\u00a0performed\u00a0\u00a0\u00a0\u00a0using Tris\/EDTA\u00a0buffer\u00a0pH\u00a09.0<\/figcaption><\/figure>\n\n\n\nHKZ150268_BP6005&BP6054_Cytokeratin 8&18<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
\n\n<\/p>\n<\/div>\n<\/div>\n\n\n\n
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\n\u6682\u65e0<\/p>\n\n\n\n
\u8bf4\u660e\u6587\u6863\u4e0b\u8f7d<\/span><\/h3>- <\/i><\/a>\u8bf4\u660e\u4e66.pdf<\/span><\/a><\/li><\/ul><\/div><\/section>\n\n\n\n
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<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":11513,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"footnotes":""},"categories":[101,99,98],"tags":[],"class_list":["post-6040","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yk","category-kt","category-products"],"metadata":{"_wp_page_template":["default"],"_wpcom_metas":["a:1:{s:11:\"show_indent\";s:1:\"0\";}"],"views":["2387"],"_canshu":["a:5:{i:0;a:5:{s:5:\"title\";s:6:\"\u4ef7\u683c\";s:4:\"text\";s:5:\"\u00a5600\";s:2:\"f1\";i:16;s:2:\"f2\";s:7:\"#e21f2f\";s:2:\"f3\";b:1;}i:1;a:5:{s:5:\"title\";s:6:\"\u89c4\u683c\";s:4:\"text\";s:5:\"100ul\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:2;a:5:{s:5:\"title\";s:6:\"\u8d27\u53f7\";s:4:\"text\";s:9:\"HKZ150268\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:3;a:5:{s:5:\"title\";s:6:\"\u5355\u4f4d\";s:4:\"text\";s:3:\"\u652f\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";b:0;}i:4;a:5:{s:5:\"title\";s:6:\"\u54c1\u724c\";s:4:\"text\";s:8:\"HaoKebio\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}}"],"catce":["sidebar-widgets4"],"_thumbnail_id":["11513"],"_dp_original":["6038"],"_edit_lock":["1732160015:2"],"_edit_last":["2"]},"medium_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016152144405.png","thumbnail_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016152144405-251x193.png","full_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016152144405.png","_links":{"self":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6040"}],"collection":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/comments?post=6040"}],"version-history":[{"count":6,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6040\/revisions"}],"predecessor-version":[{"id":12634,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6040\/revisions\/12634"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media\/11513"}],"wp:attachment":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media?parent=6040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/categories?post=6040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/tags?post=6040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- \u4ef7\u683c<\/span>\u00a5600<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150268<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150268<\/th> Cytokeratin 8&18\u5154\u5355\u514b\u9686\u6297\u4f53Cocktail<\/th> 100ul<\/th> \u652f<\/th> 600<\/th><\/tr><\/tbody><\/table> Cytokeratin\u00a08&18<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50145 Clone#\u00a0\u00a0<\/strong>BP6005&BP6054
Predicted\u00a0Molecular Wt:<\/strong>
54\/48kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P05787\/P05783
Background:<\/strong>
Cytokeratin\u00a018\u00a0is a type\u00a0Icytokeratin.\u00a0It\u00a0is, together with\u00a0its filament\u00a0partner cytokeratin\u00a08,\u00a0perhaps the\u00a0most\u00a0commonly\u00a0found\u00a0products of the\u00a0intermediate filament gene family.
In some epithelial cell types, cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0are\u00a0the\u00a0sole\u00a0keratins\u00a0present.\u00a0The\u00a0classical\u00a0example\u00a0is\u00a0the\u00a0liver,\u00a0with cytokeratin 8\/cytokeratin\u00a018\u00a0representing the characteristic and\u00a0only\u00a0keratin\u00a0pair\u00a0of\u00a0normal\u00a0hepatocytes.\u00a0The\u00a0same\u00a0is
true for other\u00a0highly specialized\u00a0parenchymatous epithelia such\u00a0asacinar\u00a0cells\u00a0of the\u00a0pancreas,\u00a0proximal\u00a0tubular\u00a0epithelial
cells of the\u00a0kidney, and certain endocrine\u00a0cells\u00a0such\u00a0as\u00a0pancreatic\u00a0islet\u00a0cells.\u00a0Furthermore,\u00a0cytokeratin\u00a08\/cytokeratin\u00a018\u00a0occur\u00a0together\u00a0with\u00a0other\u00a0keratins\u2014in\u00a0various\u00a0pseudostratified\u00a0(e.g.\u00a0respiratory) and\u00a0complex\u00a0(e.g.\u00a0glandular)\u00a0epithelia\u00a0and\u00a0in\u00a0the \u00a0\u00a0urothelium;\u00a0in these composite epithelial tissues, cytokeratin\u00a08\u00a0and\u00a0cytokeratin18\u00a0are\u00a0often\u00a0most\u00a0prominent\u00a0in the\u00a0lumen-
lining cells.\u00a0Even\u00a0in\u00a0non-keratinizing stratified squamous epithelia,\u00a0cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0may\u00a0be focally\u00a0expressed\u00a0in the\u00a0basal cell\u00a0layer, together with cytokeratin\u00a019\u00a0and the\u00a0constitutive\u00a0stratified-epithelial\u00a0keratins.
In\u00a0regard to\u00a0malignant tumors, cytokeratin 8 and\u00a0cytokeratin\u00a018\u00a0are\u00a0expressed\u00a0in\u00a0most\u00a0carcinomas\u00a0except\u00a0for\u00a0some\u00a0differentiated squamous cell carcinomas. Therefore, cytokeratin\u00a08\u00a0and\u00a0cytokeratin\u00a018\u00a0antibody\u00a0strongly\u00a0stain\u00a0most\u00a0\u00a0adenocarcinomas,\u00a0hepatocellular carcinomas,\u00a0renal cell carcinomas, and\u00a0neuroendocrine\u00a0carcinomas.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide corresponding\u00a0to cytokeratin 8
residues\u00a0within\u00a0aa383\u2010C\u00a0terminal\u00a0of\u00a0cytokeratin\u00a08\u00a0was used as\u00a0an\u00a0immunogen.
Synthetic\u00a0peptide corresponding to cytokeratin\u00a018
residues\u00a0within\u00a0aa330-430 of\u00a0cytoketatin\u00a018\u00a0was\u00a0used as an\u00a0immunogen.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Storage instructions:<\/strong>
Shipped on\u00a0blue\u00a0ice.\u00a0Upon delivery,\u00a0aliquot,\u00a0and\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0-18\u00b0C. Avoid\u00a0freeze\u00a0\/\u00a0thaw\u00a0cycles.
Recommended\u00a0Dilutions:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:50-1:100
Background\u00a0References:<\/strong>
1.\u00a0Wiedenmann\u00a0B,\u00a0et.al.\u00a0Proc\u00a0Natl\u00a0Acad\u00a0Sci\u00a0U\u00a0S\u00a0A.\u00a01986\u00a0May;83(10):3500-4.
2.\u00a0Quinn\u00a0B. Am\u00a0J\u00a0Surg\u00a0Pathol.\u00a01998\u00a0May;22(5):550-6.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed
paraffin-embedded sections)\u00a0analysis of\u00a0colon
tissue\u00a0labelling\u00a0Cytokeratin\u00a0\u00a0\u00a0\u00a08&18 with\u00a0BP6005&BP6054.\u00a0Heat\u00a0mediated\u00a0antigen
retrieval\u00a0was\u00a0performed\u00a0\u00a0\u00a0\u00a0using Tris\/EDTA\u00a0buffer\u00a0pH\u00a09.0<\/figcaption><\/figure>\n\n\n\nHKZ150268_BP6005&BP6054_Cytokeratin 8&18<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
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