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\n![\"Lambda](\"https:\/\/www.haokebio.com\/wp-content\/themes\/smartenterprise\/images\/loading.png\")
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![\"Lambda](\"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016145653949.png?imageView2\/0\/format\/webp\/q\/75\")
<\/a><\/div><\/div>\nLambda Light Chains\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div>
Lambda Light Chains\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div><\/i>\u4e00\u6297<\/a> \u6297\u4f53<\/a> \u8bd5\u5242<\/a> <\/span><\/div><\/header>- \u4ef7\u683c<\/span>\u00a5600<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150252<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150252<\/th> Lambda Light Chains\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 600<\/th><\/tr><\/tbody><\/table>Lambda\u00a0Light Chains<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50129\u00a0Clone# \u00a0<\/strong>BP6133
Predicted\u00a0Molecular Wt:<\/strong>
23kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P0CG04
Background:<\/strong>
Lambda\u00a0light chains are\u00a0polypeptide chains\u00a0located\u00a0in\u00a0the cell\u00a0membrane\u00a0and\u00a0cytoplasmic\u00a0regions\u00a0of\u00a0normal\u00a0B\u00a0cells\u00a0and
plasma cells. The combination of\u00a0lambda\u00a0light chains\u00a0and\u00a0heavy\u00a0chains\u00a0forms\u00a0immunoglobulin\u00a0molecules.\u00a0There\u00a0are\u00a0two
classes of\u00a0light chains found\u00a0in\u00a0immunoglobulins,\u00a0kappa\u00a0light chains and\u00a0lambda\u00a0light\u00a0chains.\u00a0Light\u00a0chain\u00a0production\u00a0by
lymphoid cells\u00a0is genetically\u00a0restricted such that the\u00a0immunoglobulin\u00a0molecules\u00a0produced\u00a0by\u00a0an\u00a0individual\u00a0cell will\u00a0only
contain a single\u00a0light chain class.\u00a0The\u00a0normal\u00a0human\u00a0kappa\/lambda\u00a0ratio\u00a0is\u00a0approximately\u00a02:1.\u00a0The\u00a0presence\u00a0of\u00a0clear\u00a0cut\u00a0light\u00a0chain\u00a0restriction with a\u00a0kappa\/lambda\u00a0ratio\u00a0more than\u00a010:1\u00a0is consistent with\u00a0a\u00a0malignant\u00a0proliferation.
This antibody\u00a0recognizes\u00a0lambda\u00a0light chains of\u00a0human\u00a0immunoglobulins, which\u00a0may\u00a0be\u00a0useful\u00a0in the\u00a0identification\u00a0of
leukemias,\u00a0plasmacytomas, and certain\u00a0non-Hodgkin\u2019s\u00a0lymphomas. The\u00a0most common feature\u00a0of these\u00a0malignancies\u00a0is the\u00a0restricted expression of a\u00a0single\u00a0light\u00a0chain\u00a0class.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide corresponding to\u00a0residues within\u00a0N-\u00a0terminus of\u00a0Immunoglobulin\u00a0lambda constant\u00a01 was\u00a0\u00a0\u00a0\u00a0used as\u00a0an\u00a0immunogen.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Storage instructions:<\/strong>
Shipped on\u00a0blue\u00a0ice.\u00a0Upon delivery,\u00a0aliquot,\u00a0and\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0-18\u00b0C. Avoid\u00a0freeze\u00a0\/\u00a0thaw\u00a0cycles.
Recommended\u00a0Dilutions:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1. \u00a0Kremer\u00a0M,et\u00a0al. Virchows\u00a0Arch.\u00a02005\u00a0Dec; 447(6):920-\u00a037.
2. \u00a0Marshall-Taylor\u00a0CE, et\u00a0al. Appl\u00a0Immunohistochem\u00a0Mol Morphol.\u00a02002 Sep;\u00a010(3):258-62.
Immunohistochemistry
(Formalin\/PFA-fixed
paraffin-embedded
sections)\u00a0analysis of tonsil\u00a0tissue\u00a0labelling\u00a0Lambda
Light\u00a0Chains\u00a0\u00a0with\u00a0BP6133.\u00a0Heat\u00a0mediated\u00a0antigen
retrieval was\u00a0performed\u00a0\u00a0\u00a0\u00a0using Tris\/EDTA\u00a0buffer\u00a0pH\u00a09.0\u00a0<\/figcaption><\/figure>\n\n\n\nHKZ150252_BP6133_Lambda Light Chains<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
\n\n<\/p>\n<\/div>\n<\/div>\n\n\n\n
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\n\u6682\u65e0<\/p>\n\n\n\n
\u8bf4\u660e\u6587\u6863\u4e0b\u8f7d<\/span><\/h3>- <\/i><\/a>\u8bf4\u660e\u4e66.pdf<\/span><\/a><\/li><\/ul><\/div><\/section>\n\n\n\n
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<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":11479,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"footnotes":""},"categories":[101,99,98],"tags":[],"class_list":["post-5975","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yk","category-kt","category-products"],"metadata":{"_wp_page_template":["default"],"_wpcom_metas":["a:1:{s:11:\"show_indent\";s:1:\"0\";}"],"views":["928"],"_canshu":["a:5:{i:0;a:5:{s:5:\"title\";s:6:\"\u4ef7\u683c\";s:4:\"text\";s:5:\"\u00a5600\";s:2:\"f1\";i:16;s:2:\"f2\";s:7:\"#e21f2f\";s:2:\"f3\";b:1;}i:1;a:5:{s:5:\"title\";s:6:\"\u89c4\u683c\";s:4:\"text\";s:5:\"100ul\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:2;a:5:{s:5:\"title\";s:6:\"\u8d27\u53f7\";s:4:\"text\";s:9:\"HKZ150252\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:3;a:5:{s:5:\"title\";s:6:\"\u5355\u4f4d\";s:4:\"text\";s:3:\"\u652f\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";b:0;}i:4;a:5:{s:5:\"title\";s:6:\"\u54c1\u724c\";s:4:\"text\";s:8:\"HaoKebio\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}}"],"catce":["sidebar-widgets4"],"_thumbnail_id":["11479"],"_dp_original":["5972"],"_edit_lock":["1732151814:2"],"_edit_last":["2"]},"medium_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016145653949.png","thumbnail_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016145653949-251x193.png","full_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016145653949.png","_links":{"self":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5975"}],"collection":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/comments?post=5975"}],"version-history":[{"count":6,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5975\/revisions"}],"predecessor-version":[{"id":12599,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5975\/revisions\/12599"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media\/11479"}],"wp:attachment":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media?parent=5975"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/categories?post=5975"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/tags?post=5975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- \u4ef7\u683c<\/span>\u00a5600<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150252<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150252<\/th> Lambda Light Chains\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 600<\/th><\/tr><\/tbody><\/table> Lambda\u00a0Light Chains<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50129\u00a0Clone# \u00a0<\/strong>BP6133
Predicted\u00a0Molecular Wt:<\/strong>
23kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P0CG04
Background:<\/strong>
Lambda\u00a0light chains are\u00a0polypeptide chains\u00a0located\u00a0in\u00a0the cell\u00a0membrane\u00a0and\u00a0cytoplasmic\u00a0regions\u00a0of\u00a0normal\u00a0B\u00a0cells\u00a0and
plasma cells. The combination of\u00a0lambda\u00a0light chains\u00a0and\u00a0heavy\u00a0chains\u00a0forms\u00a0immunoglobulin\u00a0molecules.\u00a0There\u00a0are\u00a0two
classes of\u00a0light chains found\u00a0in\u00a0immunoglobulins,\u00a0kappa\u00a0light chains and\u00a0lambda\u00a0light\u00a0chains.\u00a0Light\u00a0chain\u00a0production\u00a0by
lymphoid cells\u00a0is genetically\u00a0restricted such that the\u00a0immunoglobulin\u00a0molecules\u00a0produced\u00a0by\u00a0an\u00a0individual\u00a0cell will\u00a0only
contain a single\u00a0light chain class.\u00a0The\u00a0normal\u00a0human\u00a0kappa\/lambda\u00a0ratio\u00a0is\u00a0approximately\u00a02:1.\u00a0The\u00a0presence\u00a0of\u00a0clear\u00a0cut\u00a0light\u00a0chain\u00a0restriction with a\u00a0kappa\/lambda\u00a0ratio\u00a0more than\u00a010:1\u00a0is consistent with\u00a0a\u00a0malignant\u00a0proliferation.
This antibody\u00a0recognizes\u00a0lambda\u00a0light chains of\u00a0human\u00a0immunoglobulins, which\u00a0may\u00a0be\u00a0useful\u00a0in the\u00a0identification\u00a0of
leukemias,\u00a0plasmacytomas, and certain\u00a0non-Hodgkin\u2019s\u00a0lymphomas. The\u00a0most common feature\u00a0of these\u00a0malignancies\u00a0is the\u00a0restricted expression of a\u00a0single\u00a0light\u00a0chain\u00a0class.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide corresponding to\u00a0residues within\u00a0N-\u00a0terminus of\u00a0Immunoglobulin\u00a0lambda constant\u00a01 was\u00a0\u00a0\u00a0\u00a0used as\u00a0an\u00a0immunogen.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Storage instructions:<\/strong>
Shipped on\u00a0blue\u00a0ice.\u00a0Upon delivery,\u00a0aliquot,\u00a0and\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0-18\u00b0C. Avoid\u00a0freeze\u00a0\/\u00a0thaw\u00a0cycles.
Recommended\u00a0Dilutions:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1. \u00a0Kremer\u00a0M,et\u00a0al. Virchows\u00a0Arch.\u00a02005\u00a0Dec; 447(6):920-\u00a037.
2. \u00a0Marshall-Taylor\u00a0CE, et\u00a0al. Appl\u00a0Immunohistochem\u00a0Mol Morphol.\u00a02002 Sep;\u00a010(3):258-62.
Immunohistochemistry
(Formalin\/PFA-fixed
paraffin-embedded
sections)\u00a0analysis of tonsil\u00a0tissue\u00a0labelling\u00a0Lambda
Light\u00a0Chains\u00a0\u00a0with\u00a0BP6133.\u00a0Heat\u00a0mediated\u00a0antigen
retrieval was\u00a0performed\u00a0\u00a0\u00a0\u00a0using Tris\/EDTA\u00a0buffer\u00a0pH\u00a09.0\u00a0<\/figcaption><\/figure>\n\n\n\nHKZ150252_BP6133_Lambda Light Chains<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
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\u8bf4\u660e\u6587\u6863\u4e0b\u8f7d<\/span><\/h3>
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