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Claudin 6兔單克隆抗體

Claudin 6兔單克隆抗體

  • 價(jià)格￥1800
  • 規(guī)格100ul
  • 貨號(hào)HKZ150420
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150420Claudin 6兔單克隆抗體100ul支1800
Claudin?6
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50297?Clone# ?BP6274
Predicted?Molecular Wt:
23kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P56747
Background:
Claudin-6?is a?member of the CLDN family that?is?expressed?in?epithelial?cell?sheets.?Downregulation?of?Claudin-6?has?been
reported?in?breast?invasive ductal carcinoma associated with?lymphatic?metastasis which?may?point?to?a?function?of?Claudin-6
as a tumor suppressor. Claudin-6?is?reported to?play?a?role?in?inhibiting?malignancy?of?breast?cancer?cells?by?inducing?apoptosis,?inhibiting?proliferation and?migration.
Claudin6?is?rarely expressed?in?normal tissue species,?but?is?highly expressed?in tumor?cells,?especially?in?ovarian?cancer.
Subcellular?location:
Membrane & Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Shin,?K.?et?al.?(2006) Annu?Rev?Cell?Dev?Biol?22,?207-35.
2. ?Hewitt,?K.J.?et?al.?(2006)?BMC?Cancer?6,?186.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of ?human ovarian?cancer?labelling?Claudin?6????with?BP6274.

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