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- 價格¥600
- 規(guī)格100ul
- 貨號HKZ150247
- 單位支
- 品牌HaoKebio
品牌 | 商品編碼 | 商品名稱 | 規(guī)格 | 單位 | 單價 |
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HaoKebio | HKZ150247 | Calc itonin兔單克隆抗體 | 100ul | 支 | 600 |
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Calcitonin
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50124?Clone# ?BP6128
Predicted?Molecular Wt:
15.5kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P01258
Background:
Calcitonin?(CT)?is a?32 amino acid?peptide synthesized?by the?parafollicular?C?cells?of the?thyroid.?It?acts?through?its?receptors
to?inhibit osteoclast?mediated?bone?resorption, decrease calcium?resorption?by?kidney and?decrease?calcium?absorption?by
intestines. The action of calcitonin?is therefore to?cause a?reduction?in?serum?calcium,?an?effect?opposite?to?that?of?parathyroid?hormone.
The antibody?is?useful for the?identification of calcitonin-producing?C?cells and?is?a?useful?aid?for?classification?of?medullary?thyroid carcinoma.
?Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues?in?Human?Calcitonin was?used as an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Xing?R??etal.?Int?J?Mol?Med?38:1125-34?(2016).
2. ?Ramasamy?SK??et?al.?Nat?Commun?7:13601?(2016).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
medullary thyroid
carcinoma?labelling
Calcitonin?with?BP6128.??Heat?mediated?antigen???retrieval was?performed?using Tris/EDTA?buffer????pH?9.0.
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