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CD31兔多克隆抗體

CD31兔多克隆抗體

  • 價(jià)格￥2800
  • 規(guī)格200ul
  • 貨號(hào)HK210080L
  • 單位支
  • 品牌HaoKebio

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HaoKebioHK210080LCD31兔多克隆抗體200ul支2800

Applications

Tested Applications:
FC, IF, IHC, IP, WB,ELISA
Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human

Cited Species:
human, monkey

Positive WB detected in:
Jurkat cells

Positive IP detected in:
Jurkat cells

Positive IHC detected in:
human hepatocirrhosis tissue, human tonsillitis tissue, human liver cancer tissue, human gliomas tissue, human renal cell carcinoma tissue, human kidney tissue
Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

Positive IF detected in:
human tonsillitis tissue

Positive FC detected in:
HUVEC cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:800-1:4000
IF : 1:50-1:500
Product Information

Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
Immunogen Information

Full name:
platelet/endothelial cell adhesion molecule

Calculated molecular weight:
83 kDa

Observed molecular weight:
130 kDa

Gene symbol
PECAM1

Synonyms
CD31, EndoCAM, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker
Background
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

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